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Baywood's Diosmin Caps combine Diosmin and Hesperidin to
make the most complete, effective combination formula for supporting healthy
veins. Diosmin and Hesperidin are two natural citrus bioflavonoids. Both have
anti-inflammatory and antioxidant activity and support over-all cardiovascular
health, in addition to the cosmetic benefits of reducing the appearance of varicose
veins and spider veins.
Diosmin and Hesperidin are used widely in Europe for decreasing the appearance
of varicose veins and spider veins, and also hemmorhoids. Hesperidin is the
predominant flavonoid in lemons and oranges. The peel and membranous parts of
these fruits have the highest hesperidin concentrations. Hesperidin is classified
as a citrus bioflavonoid. Hesperidin, Diosmin and other flavonoids thought to
reduce capillary permeability and to have anti-inflammatory action were collectively
known as vitamin P. These substances, however, are not vitamins and are no longer
referred to, except in older literature, as vitamin P.
Like almost everything else in our bodies, our veins are susceptible to deterioration
with age, especially if we have a poor diet or inadequate exercise. This is
particularly true of the veins in our legs, which have the difficult job of
conducting blood upward against gravity's relentless pull. The movements of
the legs act as a pump to push the blood upward while flimsy valves stop gravity
from pulling it back down. However, over time these valves often begin to fail
and the blood then begins to pool in the deep veins of the leg, stretching the
vein wall and injuring its lining. This situation is called venous insufficiency.
What are Varicose Veins?
Varicose veins, a condition closely related to venous insufficiency, occur
when veins near the surface of the skin are damaged. They visibly dilate and
become distorted, resulting in a cosmetically unpleasant appearance resulting
in varicose veins and hemorrhoids (actually, the latter are varicose veins,
just in a different place), which afflict countless millions of people, especially
in Western societies, where the incidence is believed to be about 50% of all
people over 50 years of age. Researchers aren't completely sure why some veins
become varicose. Heredity is believed to play a part, as are hormones. That's
one of the reasons varicose veins may be more common in pregnancy.
In one study, distended veins improved considerably within only 60 minutes,
and the effect was still prominent four hours later (Struckmann 1994). In addition,
a Danish study showed that these amazing flavonoids were able to improve the
elasticity of veins as well as help the capillaries by reducing permeability
and leakage and support circulation (Struckmann 1999).
In Italy, a 42-day study was conducted with 40 people suffering from lower-limb
circulation problems due to unstable blood sugar levels. Researchers measured
the impact of hesperidin and diosmin on capillary filtration of albumin, a specific
protein retention and filtration problem common among those with imbalanced
blood sugar. Results showed that 55% of those taking the flavonoids achieved
completely normal capillary filtration of albumin: a remarkable success in fewer
than 45 days (Valensi 1996).
London researchers evaluated the effects of diosmin and hesperidin on 25 people
who had lost normal elasticity in their leg veins. In just four weeks, those
who received the nutrients demonstrated increased elasticity of their leg veins,
healthy blood flow, and stronger venous structure (Ibegbuna 1997).
In yet another study, people at high risk of forming traveling blood clots
were given hesperidin and diosmin both before and after undergoing major surgery.
The injection of flavonoids dramatically reduced their risk compared with those
who received a placebo (Tsimoyiannis 1996).
References
Ibegbuna, V. et al. (1997). “Venous elasticity after treatment with Daflon
500 mg.” Angiology; 48(1): 45-9.
Moore, D. (2002). “Fast facts: Blood clots.” March 18: www.drdonnica.com/display.asp?article=4671.
Struckmann, J.R. & Nicolaides, A.N. (1994). “Flavonoids: A review
of the pharmacology and therapeutic efficacy of Daflon 500 mg in patients with
chronic venous insufficiency and related disorders.” Angiology; 45(6):
419-28.
Struckmann, J.R. (1999). “Clinical efficacy of micronized purified flavonoid
fraction: An overview.” Journal of Vascular Research; 36(Suppl 1): 37-41.
Tsimoyiannis, E.C. et al. (1996). “Low-molecular-weight heparins and Daflon
for prevention of postoperative thromboembolism.” World Journal of Surgery;
20(8): 968-72.
Valensi, P.E. et al. (1996). “Effects of a purified micronized flavonoid
fraction on capillary filtration in diabetic patients.” Diabetic Medicine;
13(10): 882-8.
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